Applies only to oral form of both agents. Scopolamine decreases levels of aripiprazole by inhibition of GI absorption. Use Caution/Monitor.Īnticholinergic/sedative combos and scopolamine both decrease cholinergic effects/transmission. Scopolamine and amoxapine both decrease cholinergic effects/transmission. Scopolamine and amitriptyline both decrease cholinergic effects/transmission. Potential for increased anticholinergic adverse effects. Scopolamine and aclidinium both decrease cholinergic effects/transmission. Use of anticholinergic drugs after administration of botulinum toxin-containing products may potentiate systemic anticholinergic effects. Concomitant use with other anticholinergic-containing drugs may lead to additive anticholinergic adverse effects.ĪbobotulinumtoxinA increases effects of scopolamine by pharmacodynamic synergism. Scopolamine, umeclidinium bromide/vilanterol inhaled.Įither increases toxicity of the other by pharmacodynamic synergism. umeclidinium bromide/vilanterol inhaled. Discontinue anticholinergic drugs at least 5 half-lives before administering secretin. Concomitant use of anticholinergic drugs may cause a hyporesponse to stimulation testing with secretin. Scopolamine decreases effects of secretin by pharmacodynamic antagonism. Avoid use and monitor patients receiving the combination for effects of excessive CNS toxicity. Narcotics, hypnotics or sedatives can produce additive neuropsychiatric side effects. Ropeginterferon alfa 2b and scopolamine both increase Other (see comment). Avoid or Use Alternate Drug.Ĭomment: Avoid use of metoclopramide intranasal or interacting drug, depending on importance of drug to patient.Įither increases effects of the other by pharmacodynamic synergism. Allow sufficient washout time of drugs affecting GH release before administering macimorelin.Įither increases effects of the other by Other (see comment). Drugs that may blunt the growth hormone (GH) response to macrimorelin may impact the accuracy of the diagnostic test. Glucagon intranasal increases toxicity of scopolamine by Other (see comment). Avoid or Use Alternate Drug.Ĭomment: Coadministration of anticholinergic drugs and glucagon increase the risk of gastrointestinal adverse reactions due to additive effects on inhibition of gastrointestinal motility. Glucagon increases toxicity of scopolamine by Other (see comment).
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